Late-onset Lymphedema and Protein-losing Enteropathy with Noonan Syndrome

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Late-onset Lymphedema and Protein-losing Enteropathy with Noonan Syndrome

Noonan syndrome is characterized by facial dysmorphology, congenital heart disease and growth failure. Although it is also accompanied by deranged lymph-vessel formation, protein-losing enteropathy (PLE) with Noonan syndrome is rarely reported. We report clinical information about a boy with Noonan syndrome and late-onset lymphedema and PLE after standing for long periods of time during athleti...

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Acute onset collagenous colitis associated with protein‐losing enteropathy

Collagenous colitis is a cause of chronic diarrhea. We report an atypical case of collagenous colitis, presenting with an acute onset, and associated with protein-losing enteropathy. An 82-year-old woman was admitted with a 1 week history of nausea, appetite loss, and diarrhea. Serum albumin level was low. Protein leakage from the small intestine was found by a Technetium-99m human serum albumi...

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[Protein-losing enteropathy].

Protein-losing enteropathy (PLE) is a rare complication of intestinal diseases. Its main manifestation is hypoproteinemic edema. The diagnosis of PLE is based on the verification of protein loss into the intestinal lumen, by determining fecal α1-antitrypsin concentration and clearance. The localization of the affected colonic segment is clarified using radiologic and endoscopic techniques. The ...

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Cap polyposis with protein-losing enteropathy.

A 56-year-old male with a history of mild mental retardation, noninsulin-dependent diabetes mellitus, and hypertension presented with diarrhea and lower extremity edema of several months’ duration. The patient’s symptoms started with mild, intermittent diarrhea; several months later, his diarrhea became persistent, and he was admitted to a hospital. The patient was given metronidazole (Flagyl, ...

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Protein losing enteropathy associated with collagen diseases.

Four patients with collagen diseases are described, who developed protein losing enteropathy in the course of their disease. Their protein losing enteropathies subsided after treatment with 60 mg/day oral prednisolone. Immunohistological studies of the small intestine showed deposits of C3 in the capillary walls of villi in two patients. Increased capillary permeability due to autoimmune phenom...

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ژورنال

عنوان ژورنال: Clinical Pediatric Endocrinology

سال: 2009

ISSN: 0918-5739,1347-7358

DOI: 10.1297/cpe.18.87